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| antiplatelet drug ： ウィキペディア英語版 |
antiplatelet drug
An antiplatelet drug (antiaggregant) is a member of a class of pharmaceuticals that decrease platelet aggregation and inhibit thrombus formation. They are effective in the arterial circulation, where anticoagulants have little effect.
They are widely used in primary and secondary prevention of thrombotic cerebrovascular or cardiovascular disease.
==Choice of antiplatelet drug==
A 2006 review 〔(The American Journal of Medicine, Volume 119, Issue 8 , Pages 624-638, August 2006: ''Systematic Review and Meta-analysis of Adverse Events of Low-dose Aspirin and Clopidogrel in Randomized Controlled Trials'' ) Retrieved 2013-02-08〕 states: "...low-dose aspirin increases the risk of major bleeding 2-fold compared with placebo. However, the annual incidence of major bleeding due to low-dose aspirin is modest—only 1.3 patients per thousand higher than what is observed with placebo treatment. Treatment of approximately 800 patients with low-dose aspirin annually for cardiovascular prophylaxis will result in only 1 additional major bleeding episode."
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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